Maternal and Child Health Research Program

Office of Epidemiology and Research, Division of Research

Advancing Applied MCH Research

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Pediatric Emergency Care Applied Research Network (PECARN)

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Project Number:
Project Date: 9/30/2001

Final Report


Principal Investigator



  • Perinatal/Infancy (0-12 months)
  • Toddlerhood (13-35 months)
  • Early Childhood (3-5 years)
  • Middle Childhood (6-11 years)
  • Adolescence (12-18 years)


The PECARN was created by the Maternal and Child Health Bureau through a partnership between the Emergency Medical Services for Children (EMSC) Program and the MCH Research Program. The goal of this network is to conduct high priority, meaningful and rigorous multi-institutional research into the prevention and management of acute illnesses and injuries in children and youth across the continuum of emergency medicine health care. PECARN, comprised of four regional multi-institutional nodes (University of California, Davis; University of Michigan; Children's National Medical Center; and Columbia University) and a central data management and coordinating center (University of Utah), is the first and only federally-funded national pediatric emergency medicine research network. Each node works collaboratively with the others and with MCHB to initiate, implement, and administer network research. The four Regional Node Centers (RNCs) and their 21 Hospital Emergency Department Affiliates (HEDAs) in the PECARN network serve approximately 800,000 acutely ill and injured children every year. PECARN provides the leadership and infrastructure to conduct multi-center research studies, support research collaboration among EMSC investigators, and promote informational EMSC exchanges between EMSC investigators and providers. Principal Investigators: Nathan Kuppermann, M.D., M.P.H., University of California, Davis; Ronald F. Maio, D.O., M.S., University of Michigan; Jim Chamberlain, M.D., Children's National Medical Center; Peter Dayan, M.D., M.Sc., Columbia University; J. Michael Dean, M.D., M.B.A., University of Utah. Period of Support: 09/30/2001 - 08/31/2008 (4 Regional Nodes) 09/01/2002 - 08/31/2009 (Central Data Center)


Listed is descending order by year published.

Foltin GL, Dayan P, Tunik M, Marr M, Leonard J, Brown K, et al. Priorities for pediatric prehospital research. Pediatr Emerg Care. 2010 Oct;26(10):773-7.

Klassen TP, Acworth J, Bialy L, Black K, Chamberlain JM, Cheng N, et al. Pediatric emergency research networks: a global initiative in pediatric emergency medicine. Pediatr Emerg Care. 2010 Aug;26(8):541-3.

Chamberlain JM, Singh T, Baren JM, Maio RF; Pediatric Emergency Care Applied Research Network. Food and Drug Administration public hearing on the conduct of emergency clinnical research: testimony of Pediatric Emergency Care Applied Research Network. Acad Emerg Med. 2007 Apr;14(4):e41-2. Epub 2007 Feb 25.

Corneli HM, Zorc JJ, Mahajan P, Shaw KN, Holubkov R, Reeves SD et al; Bronchiolitis Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis. N Engl J Med. 2007 Jul 26;357(4):331-9.

Gorelick MH, Knight S, Alessandrini EA, Stanley RM, Chamberlain JM, Kuppermann N, Alpern ER; Pediatric Emergency Care Applied Research Network. Lack of agreement in pediatric emergency visit discharge diagnoses from administrative and clinical data sources. Acad Emerg Med. 2007 Jul;14(7):646-52. Epub 2007 Jun 6.

Stanley RM, Teach SJ, Mann NC, Alpern ER, Gerardi MJ, Mahajan PV, Chamberlain JM; Pediatric Emergency Care Applied Research Network. Variation in ancillary testing among pediatric asthma patients seen in emergency departments. Acad Emerg Med. 2007 Jun;14(6):532-8. Epub 2007 Apr 19.

Alpern ER, Stanley RM, Gorelick MH, Donaldson A, Knight S, Teach SJ, et al; Pediatric Emergency Care Applied Research Network. Epidemiology of a pediatric emergency medicine research network: the PECARN Core Data Project. Pediatr Emerg Care. 2006 Oct;22(10):689-99.

Dayan P, Chamberlain J, Dean JM, Maio RF, Kupperman N. The pediatric emergency care applied research network: progress and update. Clin Pediatr Emerg Med. 2006 June;7(2):128-35.

Zuspan, SJ. The pediatric emergency care applied research network. J Emerg Nurs. 2006 Aug;32(4):299-303.

Boyd RC, Le HN, Somberg R. Review of screening instruments for postpartum depression. Arch Womens Ment Health. 2005 Sep;8(3):141-53. Epub 2005 Sep 5.

Gorelick MH, Alpern ER, Singh T, Snowdon D, Holubkov R, Dean JM, et al; Pediatric Emergency Care Applied Research Network (PECARN). Availability of pediatric emergency visit data from existing data sources. Acad Emerg Med. 2005 Dec;12(12):1195-200. Epub 2005 Nov 10.


Emergency Care, Trauma & Injury

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