Office of Epidemiology and Research, Division of Research

Advancing Applied MCH Research

Grantees in the News

National Collaboration to Use Electronic Health Records to Improve Child Health

Dr. Darden

Dr. Fiks

Alexander Fiks, MD

The U.S. lacks a system to use routinely collected electronic health record (EHR) data from primary care practices to conduct comparative effectiveness research (CER) on pediatric drug therapeutics and address other high priority child health topics. An article recently published in Pediatrics details the creation of a new network of smaller EHR networks, led by the American Academy of Pediatrics Pediatric Research in Office Settings (PROS), to use clinical data from EHRs to conduct CER.To create this large network, PROS has linked EHR data from its own “ePROS” network with data from numerous independent practices and health systems across the United States. The Comparative Effectiveness Research through Collaborative Electronic Reporting (CER2) collaborators have developed a platform to advance the methodology of pediatric CER and pharmacoepidemiology. The just published article outlines the present composition, governance, challenges, opportunities and vision for using CER2 to advance child health and health care. The CER2 collaborators hope to engage child health researchers from around the United States to participate in research using the database.

MCHB Grant #: UB5MC 20286. Pediatric Primary Care Electronic Health Record (EHR) Network for Comparative Effectiveness Research (CER).

Publication: Fiks AG, Grundmeier RW, Steffes J, et al. Comparative Effectiveness Research through a Collaborative Electronic Reporting Consortium. Pediatrics. 2015 Jul;136(1):e215-224. doi: 10.1542/peds.2015-0673. Epub 2015 Jun 22. View Abstract Online. Exit Disclaimer

Why Teens Still Are Behind On Recommended Vaccines

Dr. Darden

Dr. Darden

Paul Darden, MD

Despite the fact that vaccines have been found to be a safe and effective protection against a number of vaccine-preventable adolescent diseases, many teens are still not receiving recommended vaccinations. In the study “Reasons for Not Vaccinating Adolescents: National Survey of Teens, 2008-2010,” in the April 2013 issue of Pediatrics (published online March 18), study authors analyzed the 2008-2010 National Immunization Survey of Teens to determine why parents did not have their teens up-to-date on recommended adolescent vaccines, and how these reasons have changed over the years. Parents of teens who were not vaccinated for tetanus toxoid, diphtheria toxoid, and acellular pertussis/tetanus toxoid and reduced diphtheria toxoid and quadrivalent meningococcal conjugate vaccine all gave similar reasons, including “not recommended,” and “not necessary.” These reasons remained consistent over the years for Tdap/Td and MCV4. The main reasons parents did not get the human papilloma virus (HPV) vaccine for their daughters included the same as those for the other vaccines, and also included “not sexually active,” “not appropriate age” and “safety concerns/side effects.” Concerns about safety grew each year, from 4.5 percent in 2008 to 16.4 percent in 2010. Parents’ intent not to vaccinate for HPV also increased from 39.8 percent in 2008 to 43.9 percent in 2010. Study authors conclude that despite physician recommendations, parents refusing to immunize their teens against vaccine-preventable diseases like HPV is concerning, and may require more detailed discussion about vaccine safety and effectiveness in order to improve future immunization rates.

Publication: Darden PM, Thompson DM, Roberts JR, Hale JJ, Pope C, Naifeh M, Jacobson RM. Reasons for not vaccinating adolescents: National Immunization Survey of Teens, 2008-2010. Pediatrics. 2013 Apr;131(4):645-51. doi: 10.1542/peds.2012-2384. Epub 2013 Mar 18. PubMed PMID: 23509163. View Abstract Online. Exit Disclaimer

A Push for HPV Vaccinations -
Health professionals hope to make the shots more accessible, and to make the vaccine sound less scary to parents and daughters.

Peter Milgrom
Professor, Dental Public Health Services
University of Washington

Aubrey Sheiham Award

MCH Researcher Peter Milgrom wins Aubrey Sheiham Award for Distinguished Research in Dental Public Health Sciences.

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